RecruitingPhase 1Phase 2NCT07430345

Buprenorphine for Analgesia in Older Adults With Acute Fractures in the Emergency Department

Buprenorphine for Analgesia in Older Adults With Acute Fractures in the Emergency Department: a Randomized Controlled Study


Sponsor

The Cooper Health System

Enrollment

48 participants

Start Date

May 7, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this clinical trial is to learn if buprenorphine can treat pain in older adults who have broken bones. The main questions it aims to answer are: Is buprenorphine as effective as opioids to treat pain? Are there less side effects with buprenorphine? Researchers will compare buprenorphine and hydromorphone to see if there are differences in pain control and side effects. Participants will be given one of the two study drugs after breaking a bone and asked about their pain scores and side effects for the next 48 hours.


Eligibility

Min Age: 65 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Buprenorphine 0.15 MG and a drug called Hydromorphone 0.25 mg IV for people with fracture. The study is currently recruiting participants at 1 location.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGBuprenorphine 0.15 MG

given every 15 minutes as needed for numerical pain score 4 or greater for a maximum of three doses

DRUGHydromorphone 0.25 mg IV

given every 15 minutes as needed for numerical pain score 4 or greater for a maximum of three doses


Locations(1)

Cooper University Hospital

Camden, New Jersey, United States

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NCT07430345


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