RecruitingNCT07435467

Blood Biomarkers for Alzheimer Disease and Neuro-injury to Estimate the Association With Cognitive/Functional Decline and Mortality in a Real-world Population of GERiatric Hospitalized Patients (BAD-GER)

Blood Biomarkers for Alzheimer Disease and Neuro-injury to Estimate the Association With Cognitive/Functional Decline and Mortality in a Real-world Population of GERiatric Hospitalized Patients (BAD-GER): a Multicenter, Observational, 3-arms, Prospective Study


Sponsor

Istituto Nazionale di Ricovero e Cura per Anziani

Enrollment

400 participants

Start Date

Apr 9, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

The BAD-GER study is a multicenter, prospective, three-arm observational study serving to validate a prognostic biomarker algorithm for mortality and hospital readmission; this algorithm will be developed through the retrospective analysis of Alzheimer's Disease and neurodegeneration biomarkers in an already available discovery cohort of 700 previously hospitalized geriatric patients.


Eligibility

Min Age: 65 Years

Plain Language Summary

Simplified for easier understanding

This study measures blood biomarkers related to Alzheimer's disease and brain injury in elderly hospitalised patients — whether they are in hospital for neurological conditions (like stroke or delirium) or non-neurological conditions with or without dementia — to see how these markers predict decline over time. **You may be eligible if...** - You are an older adult admitted to hospital for a stroke, delirium, epileptic seizure, or brain infection, OR - You are admitted for a non-neurological illness and have dementia, OR - You are admitted for a non-neurological illness without dementia - You or your representative can provide informed consent **You may NOT be eligible if...** - You are unwilling or unable to provide consent - Your condition does not fit one of the three groups above Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERcollection of blood samples

Serum and EDTA-plasma samples will be collected at baseline


Locations(3)

IRCCS INRCA Hospital

Ancona, Italy

IRCCS INRCA Hospital

Fermo, Italy

Policlinico Universitario

Messina, Italy

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NCT07435467


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