Wound Closure Materials and Techniques in Hip and Knee Arthroplasty
Evaluation of Different Suture Materials and Closure Techniques in Lower Extremity Arthroplasty: Effects on Wound Healing, Functional Outcomes, and Complications
Bahattin Kemah
90 participants
Nov 1, 2025
INTERVENTIONAL
Conditions
Summary
This prospective randomized clinical study aims to evaluate the effects of different suture materials and wound closure techniques on wound healing, functional outcomes, and postoperative complications in patients undergoing total hip and knee arthroplasty. A total of at least 90 adult patients undergoing primary or aseptic revision lower extremity arthroplasty will be randomized into two groups according to the wound closure material and technique used. All surgeries will be performed by the same surgical team following standardized operative protocols. Primary outcomes include wound-related complications such as prolonged wound drainage, wound dehiscence, surgical site infection, and local inflammatory findings within 90 days postoperatively. Secondary outcomes include operative time, bleeding amount, cosmetic outcomes, and functional scores. The results of this study are expected to help determine the most effective and safe wound closure method in lower extremity arthroplasty.
Eligibility
Inclusion Criteria5
- Age ≥ 30 years
- Patients undergoing primary total hip arthroplasty or total knee arthroplasty
- Patients undergoing aseptic revision total hip or knee arthroplasty
- Surgery performed by the same surgical team
- Ability to provide informed consent
Exclusion Criteria7
- Age \< 30 years
- Patients receiving immunosuppressive therapy
- Patients with complicated diabetes mellitus
- Chronic venous insufficiency
- Peripheral arterial disease
- Arthroplasty performed due to malignancy
- Active or previous surgical site infection
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Interventions
Wound closure using barbed suture material with continuous technique following total hip or knee arthroplasty.
Wound closure using conventional suture material with interrupted or standard closure technique following total hip or knee arthroplasty.
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT07439575