RecruitingNot ApplicableNCT07439575

Wound Closure Materials and Techniques in Hip and Knee Arthroplasty

Evaluation of Different Suture Materials and Closure Techniques in Lower Extremity Arthroplasty: Effects on Wound Healing, Functional Outcomes, and Complications


Sponsor

Bahattin Kemah

Enrollment

90 participants

Start Date

Nov 1, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

This prospective randomized clinical study aims to evaluate the effects of different suture materials and wound closure techniques on wound healing, functional outcomes, and postoperative complications in patients undergoing total hip and knee arthroplasty. A total of at least 90 adult patients undergoing primary or aseptic revision lower extremity arthroplasty will be randomized into two groups according to the wound closure material and technique used. All surgeries will be performed by the same surgical team following standardized operative protocols. Primary outcomes include wound-related complications such as prolonged wound drainage, wound dehiscence, surgical site infection, and local inflammatory findings within 90 days postoperatively. Secondary outcomes include operative time, bleeding amount, cosmetic outcomes, and functional scores. The results of this study are expected to help determine the most effective and safe wound closure method in lower extremity arthroplasty.


Eligibility

Min Age: 30 Years

Inclusion Criteria5

  • Age ≥ 30 years
  • Patients undergoing primary total hip arthroplasty or total knee arthroplasty
  • Patients undergoing aseptic revision total hip or knee arthroplasty
  • Surgery performed by the same surgical team
  • Ability to provide informed consent

Exclusion Criteria7

  • Age \< 30 years
  • Patients receiving immunosuppressive therapy
  • Patients with complicated diabetes mellitus
  • Chronic venous insufficiency
  • Peripheral arterial disease
  • Arthroplasty performed due to malignancy
  • Active or previous surgical site infection

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Interventions

PROCEDUREBarbed Suture Wound Closure

Wound closure using barbed suture material with continuous technique following total hip or knee arthroplasty.

PROCEDUREConventional Suture Wound Closure

Wound closure using conventional suture material with interrupted or standard closure technique following total hip or knee arthroplasty.


Locations(1)

Umraniye Training and Research Hospital

Istanbul, Istanbul, Turkey (Türkiye)

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NCT07439575


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