RecruitingNCT07441447

Evaluation of Muscle Strength and Muscle Mass in Patients With Inflammatory Bowel Disease

Evaluation of Sarcopenia in Patients With Inflammatory Bowel Disease


Sponsor

Sakarya University

Enrollment

100 participants

Start Date

Nov 10, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

This prospective observational study aims to evaluate the validity of ultrasonographic muscle measurements in patients with inflammatory bowel disease (IBD). Sarcopenia is commonly assessed using computed tomography (CT)-based skeletal muscle area measurements at the L3 vertebral level, which are considered a gold standard method. However, CT is not always feasible due to radiation exposure and accessibility limitations. In this study, muscle strength will be assessed using handgrip dynamometry, and muscle mass will be evaluated using ultrasonography of selected skeletal muscles. In patients with available recent abdominal CT imaging, L3 skeletal muscle area will be recorded. The primary objective is to compare ultrasonographic muscle measurements with CT-based assessments and to evaluate the agreement between these methods. This study aims to determine whether ultrasonography can serve as a practical and reliable alternative tool for muscle mass evaluation in patients with IBD.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is measuring muscle strength and muscle mass in people with inflammatory bowel disease (IBD) — which includes Crohn's disease and ulcerative colitis. Researchers want to understand how IBD affects muscles, using grip strength tests and ultrasound imaging, and will also look at CT scan images. **You may be eligible if...** - You are 18 or older - You have a confirmed diagnosis of Crohn's disease or ulcerative colitis - You have had an abdominal CT scan in the last 6 months - You are able to have ultrasound muscle measurements and grip strength testing - You can provide written consent **You may NOT be eligible if...** - You have a known muscle disease or nerve-muscle disorder - You have a major orthopedic condition (like a severe joint or bone problem) affecting your grip strength - You are pregnant - You have a hernia or other abdominal wall condition that would interfere with ultrasound - Your medical records or imaging data are incomplete Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DIAGNOSTIC_TESTMuscle Ultrasonography

Standardized ultrasonographic measurement of skeletal muscle thickness and quality performed in patients with inflammatory bowel disease for comparison with reference muscle assessment methods.


Locations(1)

Sakarya University Faculty of Medicine, Training and Research Hospital

Sakarya, Adapazarı, Turkey (Türkiye)

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NCT07441447


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