RecruitingNot ApplicableNCT07442851

SickleFit Exercise and Nutrition Study

The SickleFit Exercise and Nutrition Randomized Control Trial for Older Adults With Sickle Cell Disease


Sponsor

Duke University

Enrollment

40 participants

Start Date

Apr 8, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

To goal of this study is to pilot the SickleFit exercise and nutrition intervention in adults with sickle cell disease in a randomized control trial


Eligibility

Min Age: 35 Years

Inclusion Criteria3

  • Laboratory-confirmed diagnosis of sickle cell disease (any genotype)
  • Understand and speak English by self-report
  • Age ≥ 35 years old

Exclusion Criteria8

  • Oxygen dependence
  • Unstable cardiac disease
  • Wheelchair-bound
  • Diagnosed with severe cognitive impairment based on ICD-10 codes or reported by their outpatient provider
  • Unable to self-consent
  • Severe uncorrected visual or auditory impairment
  • Pregnant
  • Successfully treated with hematopoietic stem cell transplantation or gene therapy for sickle cell disease

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Interventions

BEHAVIORALSickleFit Exercise plus Nutrition

SickleFit personalized exercise plus dietitian-facilitated nutrition intervention


Locations(1)

Duke University

Durham, North Carolina, United States

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NCT07442851


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