Improving the Prognosis for Cerebral Hemorrhage A Study of Clinical, Biological, and Imaging Markers
University Hospital, Tours
10,000 participants
Apr 9, 2026
OBSERVATIONAL
Conditions
Summary
This study will establish a prospective, multicenter national cohort of patients with spontaneous intracerebral hemorrhage (ICH). A standardized multimodal database integrating clinical, biological, and imaging data will be collected. The study aims to better characterize ICH patient phenotypes, identify diagnostic and prognostic biomarkers, and describe adherence to evidence-based acute management strategies, including the proportion of patients managed according to the care bundle validated in the INTERACT 3 study. The cohort is also intended to provide a structured platform for translational research and the preparation of future stratified interventional clinical trials in spontaneous ICH.
Eligibility
Inclusion Criteria3
- Age ≥ 18 years;
- Emergency admission to a participating center, with spontaneous intracerebral hemorrhage confirmed by the first brain imaging (CT or MRI) performed at the time of initial treatment;
- Obtaining non-opposition
Exclusion Criteria8
- First brain imaging performed outside a center participating in the study (e.g., peripheral center not recruiting);
- Intracerebral hemorrhage secondary to another identified condition, including:
- vascular malformation (aneurysm, arteriovenous malformation, cavernoma, etc.);
- intracranial tumor;
- hemorrhagic transformation of a cerebral infarction;
- recent head trauma.
- Patient under legal protection;
- Patient under guardianship or conservatorship.
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Locations(4)
View Full Details on ClinicalTrials.gov
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NCT07444853