RecruitingNCT07445412

Italian Group of Regenerative and Occlusive Worldwide-used Techniques of Hepatic Hypertrophy

Italian Group of Regenerative and Occlusive Worldwide-used Techniques of Hepatic Hypertrophy - IGROWtoh


Sponsor

IRCCS Azienda Ospedaliero-Universitaria di Bologna

Enrollment

2,000 participants

Start Date

Oct 22, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

The goal of this national mutlticenter observational study is to learn and describe trends over time in the use of techniques for inducing hepatic hypertrophy in Italy. Patients will be treated according to the current clinical practice of the participating centers and will be observed from the moment of recruitment and throughout their stay. Information on vital status will be collected, as far as possible, for up to 5 years after surgery in order to record any events that occur in a timely manner. There are also plans to retrospectively collect data on patients who underwent hypertrophic techniques in the previous 10 years, in order to establish a historical cohort for each center that can be used for comparison with the prospective cohort.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is comparing different surgical techniques used to help the liver grow larger before a major liver surgery. When a patient needs part of their liver removed due to a tumor, sometimes the remaining portion is too small to sustain life — so doctors use special procedures to stimulate liver growth beforehand. This registry is tracking outcomes across different methods to find the safest and most effective approach. **You may be eligible if:** - You are 18 years of age or older - You have a liver tumor (benign or cancerous) - Your surgical team has determined that the part of your liver that would remain after surgery is too small (less than 20–40% of total liver volume) - You are willing to provide informed consent **You may NOT be eligible if:** - You are pregnant or breastfeeding Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(1)

IRCCS Azienda Ospedaliero-Universitario di Bologna

Bologna, Bologna, Italy

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NCT07445412


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