The Influence of Laser Crossectomy With Different Wavelengths on Varicose Vein Progression
Pirogov Russian National Research Medical University
400 participants
Jan 20, 2026
INTERVENTIONAL
Conditions
Summary
Technically successful laser crossectomy will reduce the risk of reflux recurrence at the sapheno-femoral junction without increasing the risk of endovenous heat-induced thrombosis, which may positively impact the likelihood of ultrasound- or clinical-recurrence of varicose veins. Similar technical efficacy is expected for laser crossectomy at 1940 nm and 1470 nm. A possible advantage of the 1940 nm wavelength in terms of postoperative pain intensity and the risk of adverse events cannot be ruled out.
Eligibility
Inclusion Criteria5
- Age >18 years
- Primary VVs of Clinical Etiology Anatomy Pathophysiology (CEAP) clinical class of C2-C6
- Reflux along the GSV trunk lasting >0.5 sec.
- GSV trunk diameter ≤12 mm
- Informed consent to participate in the study
Exclusion Criteria9
- Primary reflux outside the GSV trunk (including combined reflux)
- History of deep or superficial vein thrombosis
- Deep vein reflux
- Non-thrombotic or post-thrombotic venous obstruction
- Pelvic venous insufficiency
- Use of oral anticoagulants
- Indication for pharmacological prophylaxis after EVLT
- Inability to use radial fiber of 1.4-1.57 mm at the surgeon's discretion
- Refusal to participate in the study
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Interventions
Attempt to perform laser crossectomy with radial fiber (core of 0.4 mm, bulb of 1.57 mm) on the 1470 nm wavelength laser with a power of 6-8 W and an LED of 60-80 J/cm. Performing the GSV trunk ablation according to the indications.
Attempt to perform laser crossectomy with radial fiber (core of 0.55 mm, bulb of 1.4 mm) on the 1940 nm wavelength laser with a power of 4-6 W and an LED of 40-60 J/cm. Performing the GSV trunk ablation according to the indications.
Attempted laser crossectomy on 1470 nm or 1940 nm failed due to anatomical features of the SFJ or technical reasons, and the GSV trunk was obliterated with persistence of the stump.
Locations(1)
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NCT07449728