Assessment of the Locally Administrated Vitamin D3 and Corticision Efficacy on Orthodontic Canine Retraction
Assessment of the Locally Administrated Vitamin D3 and Corticision Efficacy on Orthodontic Canine Retraction: A Prospective Clinical Study
Al-Azhar University
16 participants
Aug 1, 2025
INTERVENTIONAL
Conditions
Summary
To study the effect vitamin D effect on orthodontic tooth movement when used in combination with coticision technique, independent t test or an equivalent non-parametric test will be used for comparison. According to a previous study by (S. T. Varughese, et al. (2019) , "Effect of vitamin D on canine distalization and alveolar bone density using multi-slice spiral CT: a randomized controlled trial
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Interventions
Administration of the Solution at eexperimental side: One milliliter of was injected into the buccal vestibule at the level of the distal margin of the root of the canine. One milliliter of (ONE ALPHA 2 MCG / ML 10 AMP 0.5 ML Leo Pharmaceutical products Ballerup - Denmark. Imported by: Egyptian Company for Drug Trading) was injected four times during treatment on the the beginning (T0), 4 weeks (T1), 8 weeks (T2), and 12 weeks (T3) of canine retraction on both sides according to Varughese, et al. " Participants were evaluated from the beginning (T0), 4 weeks (T1), 8 weeks (T2), and 12 weeks (T3) of canine distalization. At these appointments, impressions were made to obtain the study models. Multi-slice spiral computed tomography scans were taken at T0 and T3 to measure the changes in bone density following canine distalization. The primary outcome was to evaluate the rate and total amount of canine distalization as well as anchorage loss in the maxillary arch. All study measurements
Locations(1)
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NCT07455656