RecruitingNCT07457151

Danicopan PMS in Korea

Danicopan Regulatory Post-Marketing Study in Korea


Sponsor

AstraZeneca

Enrollment

8 participants

Start Date

Apr 10, 2026

Study Type

OBSERVATIONAL

Conditions

Summary

As part of a post-approval commitment, the Korean health authority requests a study to characterize safety and effectiveness in patients who are treated with Danicopan as an add-on to ravulizumab or eculizumab in normal clinical practice settings. This study is designed to assess the known safety profile or identify previously unsuspected adverse reactions and to evaluate the effectiveness of Danicopan under conditions of routine daily medical practice in Korea.


Eligibility

Inclusion Criteria2

  • Patients eligible for and treated with Danicpan as add-on therapy to a C5 inhibitor (Eculizumab or Ravulizumab) in patient with PNH in Korea
  • Provision of a signed and dated written informed consent by the patient or their legally acceptable representative

Exclusion Criteria2

  • Participation in any concurrent interventional trials during the period of study drug treatment
  • Other off-label indications according to the approved label in Korea

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Locations(4)

Research Site

Busan, South Korea

Research Site

Daegu, South Korea

Research Site

Hwasun-gun, South Korea

Research Site

Seoul, South Korea

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NCT07457151


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