RecruitingNot ApplicableNCT07460999

Singing Training vs Usual Care 6-18 Months After Surgical Resection for Non-small Cell Lung Cancer (NSCLC)

Effects and Mechanisms of Online Delivered Singing Training vs Usual Care in Patients With Persistent Symptoms 6-18 Months After Surgical Resection for Non-small Cell Lung Cancer (NSCLC) - a Multi-centre RCT

Sponsor

Zealand University Hospital

Enrollment

100 participants

Start Date

Mar 1, 2026

Study Type

INTERVENTIONAL

Summary

People who have undergone curative surgery for non-small cell lung cancer (NSCLC) often experience reduced quality of life (QoL), a high burden of symptoms, and physical deconditioning. Current Danish rehabilitation offers are heterogeneous and inconsistent and not tailored to the specific needs of this population. Additionally, some patients continue to suffer from persistent physical symptoms months or even years after surgery, yet no targeted support is currently available for them. Singing - delivered as a structured form of training - has shown benefits in improving both physical and psychological outcomes in individuals with chronic obstructive pulmonary disease (COPD). Although singing has not yet been studied in NSCLC patients, the two conditions share overlapping symptoms and characteristics. Therefore, the present study aims to explore whether a singing-based intervention can help reduce symptom burden and improve physical function and QoL in NSCLC patients 6 to 18 months post-surgery. To test this, a multi-centre randomised controlled trial (RCT) will be conducted, comparing a singing intervention to usual care. Given that travel and distance often pose significant barriers to participation, the intervention will be delivered online.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is testing whether singing lessons can help people who still have breathing or other symptoms 6 to 18 months after surgery for early-stage lung cancer. Participants do online singing sessions twice a week and researchers compare their recovery to those receiving standard care. **You may be eligible if...** - You had minimally invasive (video-assisted) surgery for stage I lung cancer 6 to 18 months ago - You still have at least one clinically significant symptom (such as breathlessness, fatigue, or pain) - You can speak and understand Danish - You have access to a computer or tablet with internet - You are motivated to participate and accept being randomly assigned to a group **You may NOT be eligible if...** - Your surgery was more than 19 months ago or fewer than 5 months ago - You do not have persistent symptoms affecting your quality of life - You lack internet access or a suitable device Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BEHAVIORALSinging training (Singing for Lung Health (SLH))

10 weeks of singing training (conducted according to the Singing for Lung Health (SLH) approach). The singing training will be delivered online (1 1/2 hour twice a week) by professional singing teachers specifically trained and experienced within SLH. Sessions include physical, vocal, and breathing exercises and musical repertoire. Besides, movement, dancing, and artefacts for playful games are included along with singing. Each session consists of 20 min physical warm-ups, 20 min vocal warm-up with rhythm and pitch games, 40 min singing (incl. break), and 10 min cool-down.

BEHAVIORALControl group: Usual care

The control group will receive usual care, i.e., no specific additional intervention above those which the person usually engages with.

Locations(5)

August Krogh Section for Molecular and Human Physiology, Department of Nutrition, Exercise, and Sports, Faculty of Health and Medical Sciences, University of Copenhagen

Copenhagen, Denmark

Department of Respiratory Medicine, Bispebjerg Hospital

Copenhagen, Denmark

Department of Medicine Roskilde and Næstved, Zealand University Hospital

Næstved, Denmark

Department of Respiratory Medicine, Odense University Hospital

Odense, Denmark

Department of Respiratory Medicine, Lillebaelt Hospital

Vejle, Denmark

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NCT07460999