RecruitingNCT07463872

Management of Pancreatic Cystic Lesions Using Artificial Intelligence Based on EUS and Multimodal Data

A Multimodal Artificial Intelligence Model for Subtyping Diagnosis and Clinical Management of Pancreatic Cystic Lesions Based on Endoscopic Ultrasound and Clinical Information


Sponsor

Huazhong University of Science and Technology

Enrollment

500 participants

Start Date

Jan 1, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

The primary objective is to construct a multimodal AI model (Cyst-AI) based on EUS images and clinical data such as imaging features(CT or MRI) and laboratory tests to assist endoscopists in the diagnosis of pancreatic cystic lesions(PCLs), mainly differentiating mucinous from non-mucinous lesions. The secondary objective is to evaluate the model's effectiveness in risk stratification and clinical management for patients with PCLs.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is using artificial intelligence to analyze ultrasound images (EUS — endoscopic ultrasound) of cysts in the pancreas to better classify whether they are dangerous or benign. The pancreas can develop fluid-filled sacs (cysts) that range from harmless to potentially cancerous, and this study aims to improve how accurately doctors can tell the difference. **You may be eligible if...** - You have had an endoscopic ultrasound (EUS) that detected a pancreatic cyst - Your cyst is a mucinous type (MCN or IPMN) or non-mucinous type (pseudocyst, serous, or cystic neuroendocrine tumor) **You may NOT be eligible if...** - You are under 18 years old - You have already had pancreatic surgery before the EUS - You have received chemotherapy or radiation for a pancreatic tumor before the EUS - Your cyst is a metastasis (spread) from another cancer - Your ultrasound images are missing or too poor quality for review Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DIAGNOSTIC_TESTCyst-AI model

The multi-center collected data will be divided into a training set, a validation set, and a test set for developing and testing the cyst-AI model.


Locations(2)

Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology

Wuhan, Hubei, China

Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology

Wuhan, Hubei, China

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NCT07463872


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