RecruitingNot ApplicableNCT07464093

STABLE Pilates for Hypermobility

Pilates for Hypermobility: A Pilot Feasibility Study


Sponsor

Brigham and Women's Hospital

Enrollment

100 participants

Start Date

Jul 1, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

This study is looking at whether Pilates-based exercise can help with hypermobility-related symptoms, like pain.


Eligibility

Min Age: 18 Years

Inclusion Criteria7

  • ≥ 18 years old;
  • Self-reported hypermobility with confirmed or suspected diagnosis of hEDS/HSD;
  • Self-reported persistent pain ≥ 3 months;
  • A minimum of 3/10 self-reported pain intensity in the past week
  • Able to get on and off the floor without assistance;
  • Able to communicate fluently in English; and
  • Able to provide written, informed consent

Exclusion Criteria8

  • Regular ongoing mind-body practice (e.g. Tai chi, yoga, pilates) defined as a regular weekly practice of at least 20min/week over the past 6 months;
  • Recent surgery or acute bone, joint or nerve injury (<6 months);
  • Have a history of a severe or progressive neurological or movement disorder;
  • Pregnant, planning to become pregnant during the study, or currently breast feeding;
  • Unable to get on and off the floor without assistance;
  • Unable to complete study procedures due to cognitive impairment;
  • Unable to provide written, informed consent; or
  • Currently participating in or planning to participate in another physical activity, mind-body or pain-related intervention research study in the next 4 months.

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Interventions

BEHAVIORALPilates

Pilates is a gentle mind-body exercise with an emphasis on muscular control, postural awareness, and breathing that may be particularly well-suited for managing hypermobility. Exercises are mostly floor-based and focus on developing muscular strength and stability which may improve pain and symptom management

BEHAVIORALEducation

Educational seminars pertaining to hypermobility symptom management


Locations(1)

Brigham and Women's Hospital

Chestnut Hill, Massachusetts, United States

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NCT07464093


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