RecruitingPhase 1NCT07465835
A Study of ELA026 in Participants With Relapsed/Refractory (R/R) T/NK Cell Malignancies (TCMs)
Sponsor
Electra Therapeutics Inc.
Enrollment
84 participants
Start Date
Feb 17, 2026
Study Type
INTERVENTIONAL
Summary
This is a Phase 1, two-part, multicenter study to evaluate ELA026 in participants ≥18 years old with relapsed/refractory TCM following any line of prior therapy who are eligible for investigational treatments.
Eligibility
Min Age: 18 Years
Plain Language Summary
Simplified for easier understanding
This study is testing a new investigational drug called ELA026 in people with T-cell or NK-cell blood cancers (called T/NK cell malignancies) that have come back or stopped responding to prior treatment. These are rare and aggressive blood cancers, and ELA026 works through a novel mechanism targeting these cancer cells.
**You may be eligible if...**
- You are 18 years or older
- You have a confirmed diagnosis of a T-cell or NK-cell malignancy
- Your cancer has relapsed or is refractory (not responding) to prior therapy
- For cutaneous T-cell lymphoma: you have tried at least 2 prior systemic treatments
- You have measurable disease and are reasonably functional (ECOG ≤2)
- Your expected survival is more than 6 months
**You may NOT be eligible if...**
- A standard approved treatment with established benefit is still available for you
- You have significant organ dysfunction
- You do not meet other health requirements defined in the protocol
Talk to your doctor to see if this trial is right for you.
This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.
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Interventions
DRUGELA026
Weekly maintenance dosing via subcutaneous injection
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT07465835