RecruitingPhase 1NCT07465835

A Study of ELA026 in Participants With Relapsed/Refractory (R/R) T/NK Cell Malignancies (TCMs)


Sponsor

Electra Therapeutics Inc.

Enrollment

84 participants

Start Date

Feb 17, 2026

Study Type

INTERVENTIONAL

Summary

This is a Phase 1, two-part, multicenter study to evaluate ELA026 in participants ≥18 years old with relapsed/refractory TCM following any line of prior therapy who are eligible for investigational treatments.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is testing a new investigational drug called ELA026 in people with T-cell or NK-cell blood cancers (called T/NK cell malignancies) that have come back or stopped responding to prior treatment. These are rare and aggressive blood cancers, and ELA026 works through a novel mechanism targeting these cancer cells. **You may be eligible if...** - You are 18 years or older - You have a confirmed diagnosis of a T-cell or NK-cell malignancy - Your cancer has relapsed or is refractory (not responding) to prior therapy - For cutaneous T-cell lymphoma: you have tried at least 2 prior systemic treatments - You have measurable disease and are reasonably functional (ECOG ≤2) - Your expected survival is more than 6 months **You may NOT be eligible if...** - A standard approved treatment with established benefit is still available for you - You have significant organ dysfunction - You do not meet other health requirements defined in the protocol Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGELA026

Weekly maintenance dosing via subcutaneous injection


Locations(1)

START, Midwest

Grand Rapids, Michigan, United States

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NCT07465835