ClinicalTrialsFinder
RecruitingPhase 3NCT07467213

Routine Use of Potassium Competitive Acid Blocker vs. Guideline-Directed Gastrointestinal Protection Strategy in Acute Myocardial Infarction

Routine Use of Potassium Competitive Acid Blocker Versus Guideline-Directed Gastrointestinal Protection Strategy in Patients With Acute Myocardial Infarction Undergoing Percutaneous Coronary Intervention on Dual Antiplatelet Therapy: A Randomized Trial

Sponsor

Samsung Medical Center

Enrollment

5,000 participants

Start Date

Jun 23, 2026

Study Type

INTERVENTIONAL

Conditions

Gastrointestinal BleedingAcute Myocardial Infarction (AMI)

Summary

This study aims to compare the clinical outcomes between routine use of potassium competitive acid blocker (P-CAB) and guideline-directed gastrointestinal (GI) protection strategy in patients with acute myocardial infarction (AMI) undergoing percutaneous coronary intervention (PCI) and being treated with dual antiplatelet therapy (DAPT).

Eligibility

Min Age: 19 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Proton Pump Inhibitors (PPI) and a drug called Zastaprazan for people with acute myocardial infarction (ami) and gastrointestinal bleeding. The study is currently recruiting participants at 1 location. People eligible for this study include aged 19 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

DRUGZastaprazan

Zastaprazan citrate 20mg will be administered orally once daily for gastrointestinal protection according to the study protocol.

DRUGProton Pump Inhibitors (PPI)

Guideline-directed gastrointestinal protection using various proton pump inhibitors as determined by the physician.

Locations(1)

Samsung Medical center

Seoul, South Korea

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT07467213

Related Trials

Comprehensive HHT Outcomes Registry of the United States (CHORUS)

NCT0625929216 locations

Magenta Elevate™ Clinical Feasibility Study in Cardiogenic Shock

NCT072939238 locations

Non-stenting Treatment Strategy for Acute Myocardial Infarction With Non-severe Stenosis(EROSION IV)

NCT0756762548 locations

Tegoprazan for Prevention of Gastrointestinal Complication in Ischemic Stroke Patients on Antiplatelet Therapy (TegoStroke)

NCT0768770624 locations

Marginal Ulcer Healing With Low-Thermal Argon Plasma Endoscopic Treatment

NCT065433161 location