RecruitingNCT07467382

GOAT (Gait Observation of Achilles Tendon)

Characterization of Mechanical Properties of Achilles Tendon During Gait in Spastic Paresis Syndrome


Sponsor

Nantes University Hospital

Enrollment

60 participants

Start Date

Jun 1, 2026

Study Type

OBSERVATIONAL

Conditions

Summary

The purpose of this study is to evaluate the mechanical properties of the Achilles tendon (stiffness, length, volume) and the force production capacities of the gastrocnemius medialis muscle in patients with spastic paresis (post-stroke or incomplete spinal cord injury) compared to healthy subjects, during gait.


Eligibility

Min Age: 18 Years

Inclusion Criteria18

  • Study population:
  • Cognitive abilities compatible with the experiment: no language or judgement disorders preventing understanding of the research or expression of consent. An aphasia severity score greater than or equal to 3 on the Boston Diagnostic Aphasia Examination (BDAE) scale will be required for inclusion.
  • Post-stroke population:
  • Adult male or female
  • Patient who has had a stroke > 7 days ago
  • Patient hospitalised (in conventional hospitalisation or day hospital) in the neurological physical and medical rehabilitation department of Nantes University Hospital
  • Patients with voluntary motor function rated between 2 and 4 on the MRC (Medical Research Council) scale at the GM level
  • Patients classified as 3 to 8 on the New Functional Ambulation Classification
  • Indication to perform a quantified gait analysis as part of clinical management
  • Post-spinal cord injury population:
  • Adult men or women
  • Patients with incomplete spinal cord injury graded ASIA AIS C or D from C2 to L5
  • Patients hospitalised (in conventional hospitalisation or day hospital) in the neurological physical and occupational therapy department of Nantes University Hospital
  • Patients with voluntary motor function rated between 2 and 4 on the MRC (Medical Research Council) scale at GM level
  • Patients rated 13-20 on the WISCI-II scale
  • Indication for a quantified gait analysis as part of clinical care
  • Healthy population:
  • Adult men or women with no nervous system disorders.

Exclusion Criteria9

  • Post-stroke and post-spinal cord injury population:
  • Minors;
  • History of calf surgery, surgery to reduce triceps surae spasticity, or intramuscular injection (e.g. botulinum toxin) in the plantar flexors < 6 months;
  • Patients with a progressive condition that contraindicates exertion (syrinx, cardiovascular instability);
  • Peripheral pathology of the lower limb in question.
  • Healthy population:
  • History of calf surgery;
  • History of muscle injury, fracture or sprain of the lower limb < 3 months;
  • History of neurological condition.

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Interventions

DIAGNOSTIC_TEST3D Gait Analysis

Evaluation includes maximal and sub-maximal isometric plantar flexion on a dynamometer with electrical stimulation, 3D quantified gait analysis synchronized with surface electromyography and ultrasound, and 3D ultrasound volume acquisition.

DIAGNOSTIC_TESTUltrasound

Evaluation includes maximal and sub-maximal isometric plantar flexion on a dynamometer with electrical stimulation, 3D quantified gait analysis synchronized with surface electromyography and ultrasound, and 3D ultrasound volume acquisition.

DIAGNOSTIC_TESTDynamometry

Evaluation includes maximal and sub-maximal isometric plantar flexion on a dynamometer with electrical stimulation, 3D quantified gait analysis synchronized with surface electromyography and ultrasound, and 3D ultrasound volume acquisition.


Locations(1)

CHU de Nantes

Nantes, France

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NCT07467382


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