RecruitingNot ApplicableNCT07468903

Focal Radiation Therapy (HDR-Brachytherapy) for the Treatment of Prostate Cancer

Phase II Trial of Focal Radiation Therapy in Patients With Prostate Cancer


Sponsor

Jonsson Comprehensive Cancer Center

Enrollment

45 participants

Start Date

May 11, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

This clinical trial tests the effect of focal radiation therapy, high dose rate-brachytherapy (HDR-BT), in treating patients with prostate cancer. Prostate cancer is the most diagnosed cancer in men and there are many treatments available, including surgery and radiation therapy. Although surgery and radiation therapy improve survival urinary and sexual function can be significantly affected and can be long lasting. HDR-BT, a type of focal radiation therapy also known as internal radiation therapy, uses radioactive material placed directly into or near a tumor to kill tumor cells. Giving HDR-BT may be effective in providing local control while reducing side effects in patients with prostate cancer.


Eligibility

Sex: MALEMin Age: 40 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying Biopsy Procedure, a procedure called Biospecimen Collection, and others for people with prostate adenocarcinoma, stage i prostate cancer american joint committee on cancer (ajcc) v8, and other related conditions. The study is currently recruiting participants at 1 location. People eligible for this study include men aged 40 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

PROCEDUREBiopsy Procedure

Undergo tumor biopsy

PROCEDUREBiospecimen Collection

Undergo blood sample collection

RADIATIONHigh-Dose Rate Brachytherapy

Undergo HDR-BT

PROCEDUREMultiparametric Magnetic Resonance Imaging

Undergo mpMRI

PROCEDUREPSMA PET Scan

Undergo PSMA PET

OTHERQuestionnaire Administration

Ancillary studies


Locations(1)

UCLA / Jonsson Comprehensive Cancer Center

Los Angeles, California, United States

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NCT07468903


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