RecruitingPhase 2NCT07473700

Study of TX000045 in Participants With Pulmonary Hypertension Due to Interstitial Lung Disease

An Open-Label Study to Assess the Hemodynamic Effect and the Safety of TX000045 After 16 Weeks of Treatment in Participants With Pulmonary Hypertension Due to Interstitial Lung Disease

Sponsor

Tectonic Operating Company, Inc.

Enrollment

25 participants

Start Date

Aug 1, 2026

Study Type

INTERVENTIONAL

Conditions

Lung Diseases, Interstitial Hypertension, Pulmonary

Summary

The primary purpose of this study is to assess the effect of TX000045 on pulmonary vascular resistance (PVR) in participants with pulmonary hypertension secondary to interstitial lung disease (PH-ILD) and to assess the safety and tolerability of TX000045 in participants with PH-ILD.

Eligibility

Min Age: 18 YearsMax Age: 80 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called TX000045 for people with hypertension, pulmonary and lung diseases, interstitial. The study is currently recruiting participants at 16 locations. People eligible for this study include aged 18 Years to 80 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

DRUGTX000045

Subcutaneous Injection.

Locations(16)

Phoenix

Phoenix, Arizona, United States

San Francisco

San Francisco, California, United States

Idaho

Idaho Falls, Idaho, United States

Allen Park

Allen Park, Michigan, United States

Krakow

Krakow, Poland

Lublin

Lublin, Poland

Wroclaw

Wroclaw, Poland

Bucharest

Bucharest, Romania

Belgrade

Belgrade, Serbia

Sremska Kamenica

Kamenitz, Serbia

Niš

Niš, Serbia

Gyeonggi-Do

Gyeonggi-do, South Korea

Seoul

Seoul, South Korea

Barcelona

Barcelona, Spain

Madrid

Madrid, Spain

Santander

Santander, Spain

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT07473700

Related Trials

A Study Providing Treatment Access in Participants With Pulmonary Hypertension Completing a Parent Study and Having no Other Option

NCT0517987645 locations

H01 in Adults With Interstitial Lung Disease (The SOLIS Study)

NCT063256961 location

Deep Learning Detection of Pulmonary Hypertension and Low Ejection Fraction Via Digital Stethoscope and 3-Lead ECG

NCT070876134 locations

Extension Study of Sotatercept in People With Pulmonary Hypertension (MK-7962-023)

NCT0681414557 locations

Connective Tissue Disease-associated Interstitial Lung Diseases (CTD-ILD) Epidemiology Non-interventional Study (NIS)

NCT058193851 location