Preoperative Clindamycin Vaginal Cream Versus Vaginal Cleansing With Povidone-iodine on Postoperative Infections After Cesarean Section
Comparative Study of the Effect of Preoperative Clindamycin Vaginal Cream Versus Vaginal Cleansing With Povidone-iodine on Postoperative Infections After Cesarean Section
Beni-Suef University
150 participants
Sep 20, 2025
INTERVENTIONAL
Conditions
Summary
To evaluate the effects of preoperative prophylactic administration of clindamycin vaginal cream compared to preoperative vaginal cleansing using a 10% povidone-iodine solution on postpartum infectious morbidity.
Eligibility
Inclusion Criteria4
- female participants with singleton pregnancies scheduled for elective cesarean sections at term, specifically between 37 and 40 weeks of gestation
- free from any medical disorders.
- The participants' ages ranged from 18 to 40 years
- body mass index (BMI) ranged from 18 to 30 kg/m2
Exclusion Criteria7
- Cases of urgent or emergent CS.
- Abnormal vaginal secretion (bad smelling yellowish secretion, whitish cheesy discharge with pruritus, bloody discharge; etc…).
- Women with medical disorders such as pre-gestational diabetes, anemia, hypertension, preeclampsia, or immunosuppressant pregnant women.
- Women who had a skin infection adjacent to the operative site.
- Allergy to topical povidone-iodine or clindamycin
- Feverish patients or history of premature rupture of membranes or with placenta previa.
- patients lost during follow-up were excluded from the final analysis.
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Interventions
Clindamycin vaginal cream one applicator each night for 3 nights before CS.
Vaginal preparation with povidone- iodide solution 10 %
Locations(1)
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NCT07474194