cfMSC Stem Cell Therapy Targeting COPD

This study is testing a stem cell therapy using a type of cell called "cord-blood-derived mesenchymal stem cells" (cfMSC) to treat moderate to severe COPD — a chronic lung disease that causes breathing difficulties. Standard medications have not been effective enough for some patients, and this trial is exploring whether stem cells can help repair and reduce lung inflammation. **You may be eligible if...** - You are between 40 and 80 years old - You have moderate to severe COPD (confirmed by breathing tests) - You have been on standard COPD medications for at least 3 months with stable symptoms - Standard treatments have not worked well enough for you - You have not smoked for at least 6 months and agree to stay smoke-free during the study - Your life expectancy is greater than 6 months **You may NOT be eligible if...** - You have other serious lung conditions like asthma, active tuberculosis, or pulmonary embolism - You had lung surgery in the past year - You had a severe COPD flare-up or were on a breathing machine in the past 4 weeks - You have HIV, hepatitis C, or syphilis - You have or have had cancer - You have an autoimmune disease requiring long-term steroids - You are pregnant Talk to your doctor to see if this trial is right for you.