RecruitingPhase 1NCT07477743

A Phase Ib Clinical Study on the Safety and Efficacy of HC010 Combinations in Advanced Solid Tumors

Phase Ib Study to Evaluate the Tolerability, Safety, Pharmacokinetics and Preliminary Efficacy of HC010 Combinations in Patients With Advanced Solid Tumors and Determine the Recommended Dose for Subsequent Studies.


Sponsor

HC Biopharma Inc.

Enrollment

331 participants

Start Date

Mar 17, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

Phase Ib study to evaluate the tolerability, safety, pharmacokinetics and preliminary efficacy of HC010 in combination with chemotherapy regimens in patients with advanced gastrointestinal cancer and determine the recommended dose for subsequent studies.


Eligibility

Min Age: 18 YearsMax Age: 75 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Capecitabine, a drug called HC006, and others for people with advanced solid tumor cancer. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years to 75 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGHC010

HC010 once every 3 weeks (Q3W) by intravenous drip

DRUGPaclitaxel

the combination chemotherapy regimens are all commonly used in clinical practice

DRUGOxaliplatin

the combination chemotherapy regimens are all commonly used in clinical practice

DRUGCapecitabine

the combination chemotherapy regimens are all commonly used in clinical practice

DRUGHC006

HC006 once every 3 weeks (Q3W) by intravenous drip


Locations(1)

Beijing Cancer Hospital

Beijing, China

View Full Details on ClinicalTrials.gov

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NCT07477743


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