RecruitingPhase 1NCT07478848

Radiation, Oral Vancomycin, and CAR-T for B-Cell Lymphomas

A Pilot Trial of Bridging Radiation Therapy With Oral Vancomycin for Patients With B-cell Lymphomas Undergoing CAR-T Therapy

Sponsor

Abramson Cancer Center at Penn Medicine

Enrollment

14 participants

Start Date

May 29, 2026

Study Type

INTERVENTIONAL

Conditions

Diffuse Large B-Cell Lymphoma (DLBCL)Large B-cell Lymphoma Non-Hodgkin Lymphoma (NHL)Diffuse Large B Cell Lymphoma Refractory Diffuse Large B Cell Lymphoma Relapsed

Summary

This clinical trial assesses whether it is feasible to use radiation therapy with vancomycin prior to CAR T-cell therapy for patients with large B-cell lymphomas

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a biological treatment called CAR-T, Radiation Therapy, and others for people with diffuse large b cell lymphoma refractory, diffuse large b cell lymphoma relapsed, and other related conditions. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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