Progel Platinum for Air Leak Reduction After VATS Lobectomy for NSCLC

This study is testing a sealant product called Progel Platinum to see if it can reduce air leaks after minimally invasive lung surgery (video-assisted thoracoscopic surgery, or VATS) to remove a lobe of the lung in patients with non-small cell lung cancer. Air leaks after lung surgery are a common complication that prolongs hospital stays. **You may be eligible if...** - You are 18 or older - You are scheduled for minimally invasive (VATS) removal of an upper or lower lung lobe for non-small cell lung cancer - You have given written informed consent **You may NOT be eligible if...** - You received chemotherapy, immunotherapy, or radiation before your surgery - You have severe COPD (GOLD stage 3 or higher) - You have an allergy or intolerance to albumin (a protein used in the sealant) - You have kidney problems - You are having a more extensive surgery (e.g., involving the chest wall or heart lining) - You have had prior lung surgery (redo surgery) - You are expected to have extensive scar tissue in the chest Talk to your doctor to see if this trial is right for you.