RecruitingNCT07481526

A Prospecitve Multicenter, Observational Registry Study

A Multicenter Real-World Registry of Characteristics, Treatment Strategies, and Clinical Outcomes in Chinese Adults With Chronic Kidney Disease


Sponsor

AstraZeneca

Enrollment

3,000 participants

Start Date

Feb 27, 2026

Study Type

OBSERVATIONAL

Conditions

Summary

This is a prospective, multicenter, observational registry study designed to collect data to deepen the understanding of CKD therapeutics, changes in clinical practice, cardiorenal risk outcomes and differences in treatment approaches in Chinese CKD patients.


Eligibility

Inclusion Criteria5

  • Male or female patients aged ≥18 years.
  • Willing and able to provide written informed consent to participate in the study.
  • Confirmed CKD diagnosis at enrolment, defined by at least one of the following:
  • eGFR \<60 mL/min/1.73 m² for ≥3 months, OR
  • Evidence of kidney damage (e.g., UACR ≥30 mg/g or UPCR ≥150 mg/g, structural abnormality on imaging, or kidney biopsy findings consistent with chronic kidney injury) persisting for ≥3 months

Exclusion Criteria5

  • Having a life-threatening comorbidity with life expectancy \< 2 years.
  • Severe cardiac disease: life-threatening arrhythmias, or recent MACE (Myocardial infarction (MI), stroke, CV death) within the past 3 months.
  • Pregnant or breastfeeding women.
  • Currently enrolled in any interventional clinical trial or receiving investigational therapy within 3 months of enrollment.
  • Presenting with ESRD, RRT, acute kidney injury (AKI), acute kidney disease (i.e., kidney injury or a decline in renal function persisting for ≤3 months) as a primary disease condition at enrollment.

Locations(1)

Zhongshan Hospital Affilicated with Fudan University

Shanghai, China

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NCT07481526


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