RecruitingNCT07483853

Reliability and Validation of the WB-MRI Radiological Score in CRMO

Reliability and Validation of the WB-MRI Radiological Score in CRMO: Retrospective Observational Study in Paediatric Patients


Sponsor

IRCCS Azienda Ospedaliero-Universitaria di Bologna

Enrollment

15 participants

Start Date

Jan 1, 2027

Study Type

OBSERVATIONAL

Conditions

Summary

This study evaluates the inter-observer reliability of a standardized WB-MRI scoring system for CRMO and its consistency with the PedCNO clinical score. It also investigates whether changes in the radiologic score mirror therapeutic response, supporting a more objective clinical-radiological disease assessment.


Eligibility

Max Age: 32 Years

Inclusion Criteria5

  • Patients with a diagnosis of CRMO according to the international Bristol clinical and radiologic criteria, followed at the Pediatric Rheumatology Clinic of the Pediatric Unit, IRCCS AOU Bologna, Sant'Orsola Hospital;
  • Age under 18 years at the time of CRMO diagnosis;
  • At least one WB-MRI performed as part of routine clinical follow-up between January 2015 and the start date of the study;
  • Availability of complete clinical documentation (including reports, radiologic images, and clinical information) sufficient to apply both the WB-MRI score and the PedCNO score;
  • Obtain informed consent.

Exclusion Criteria1

  • \- Alternative diagnoses accounting for the bone lesions (e.g., infections, neoplasms).

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Locations(1)

IRCCS Azienda Ospedaliero-Universitaria di Bologna

Bologna, Italy

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NCT07483853


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