Artificial Intelligence in Aortic Regurgitation
Artificial Intelligence in Aortic Regurgitation: A Multicenter Randomised Controlled Trial
Chinese University of Hong Kong
540 participants
Dec 1, 2025
INTERVENTIONAL
Conditions
Summary
This research project aims to develop and validate a tool that uses artificial intelligence (AI) to automatically detect and quantify aortic regurgitation (AR). The clinical efficacy of this tool will be established by comparing it to manual diagnostic methods in a multicenter randomized controlled trial. By leveraging deep learning (DL) techniques, the AI system will automate aortic regurgitation (AR) detection, measurement, and diagnosis, addressing challenges like variability in echocardiographic interpretations and the need for specialized expertise. It will integrate multiple echocardiographic parameters to provide accurate, standardized, and efficient AR diagnoses, reducing human error and improving consistency. This tool will enhance diagnostic precision and accessibility, improving clinical outcomes and extending advanced diagnostic capabilities to a broader range of healthcare environments, including resource-limited settings.
Eligibility
Inclusion Criteria3
- Confirmed AR diagnosis via TTE and Doppler imaging per guidelines.
- Age ≥ 18 years.
- Adequate acoustic window for AR quantification.
Exclusion Criteria3
- Prior cardiac transplant or implanted cardiac devices.
- Poor image quality.
- Pregnancy or lactation.
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Interventions
Participants in this group will undergo aortic regurgitation assessment using an advanced artificial intelligence tool.
Participants in this group will receive a traditional diagnostic assessment for aortic regurgitation, performed by trained sonographers following standard protocols.
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT07486271