RecruitingNCT07487350

Recurrent Visceral Leishmaniasis in HIV Co-Infection

New And Recurrent Visceral Leishmaniasis in HIV Co-Infected Ethiopian Patients: a Cohort Study


Sponsor

Institute of Tropical Medicine, Belgium

Enrollment

20 participants

Start Date

Oct 21, 2025

Study Type

OBSERVATIONAL

Summary

The aim is (1) to better understand the underlying causes and predispositions for relapse and parasite persistence in visceral leishmaniasis (VL) patients living with HIV and (2) to improve treatment monitoring of this target group in Ethiopia


Eligibility

Min Age: 18 Years

Inclusion Criteria2

  • VL-HIV infection 1.1. VL: microscopically confirmed parasite presence in spleen or bone marrow tissue at first episode or relapse; for known active chronic cases: decision to treat VL 1.2. HIV: confirmed viral infection (new or past)
  • ≥18 years

Exclusion Criteria3

  • Not willing to provide written informed consent
  • Not willing to adhere to the follow-up visits
  • Mentally or physically incapable to participate in the study (to the discretion of the treating physician)

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Locations(1)

University of Gondar

Gonder, Ethiopia

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NCT07487350