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RecruitingNot ApplicableNCT07488091

Multi Disciplinary Sickle Cell Disease Obstetrics Care Program in Ghana

Multi Disciplinary Sickle Cell Disease Obstetrics Care Program in Ghana: Non-academic vs Academic Hospital (Pilot Study)

Sponsor

University of Ghana Medical School

Enrollment

198 participants

Start Date

Jan 22, 2026

Study Type

INTERVENTIONAL

Conditions

Sickle Cell Disease and Pregnancy

Summary

The goal of this observational study is to determine the feasibility and effectiveness of initiating a multidisciplinary sickle cell disease (SCD) obstetrics program for women with SCD in a non-academic hospital. The main question it aims to answer is: In a before-and-after study design, we will test the hypothesis that multidisciplinary care for pregnant women with SCD in a non-academic hospital will result in a 50% relative risk reduction in mortality compared to the mortality rate in pregnant women with SCD in the same hospital before the multidisciplinary care. Participants will be managed using the academic hospital's multidisciplinary sickle cell disease obstetrics protocol adapted for the non-academic hospital

Eligibility

Sex: FEMALEMin Age: 18 YearsMax Age: 45 Years

Inclusion Criteria5

  • Pregnant women with a confirmed laboratory diagnosis of sickle cell disease
  • Pregnancy confirmed by a pelvic ultrasound scan
  • Pregnancy should be 34 weeks' gestation or less
  • Pregnant women should be aged 18 - 45 years
  • Pregnant women should be attendants at the non-academic hospital

Exclusion Criteria4

  • All pregnant women with sickle cell disease who do not provide informed consent
  • All pregnant women with sickle cell disease who are referred for management of acute complications and hospital admission
  • All pregnant women with sickle cell disease who are referred for labor and delivery
  • All pregnant women with SCD who plan on delivering outside the non-academic hospital and won't be able to adhere to the follow-up procedures during the puerperium (the first six weeks after childbirth)
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Interventions

OTHERMultidisciplinary sickle cell disease (SCD) obstetrics program for women with SCD in a non-academic hospital.

Pregnant women with sickle cell disease

Locations(1)

Greater Accra Regional Hospital

Accra, Ghana

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NCT07488091