RecruitingPhase 2NCT07490444

Metric-Optimized Spectacle Prescriptions for Children With Down Syndrome

Metric-derived Corrections Versus Clinically-derived Corrections for Children With Down Syndrome

Sponsor

Ohio State University

Enrollment

24 participants

Start Date

May 26, 2026

Study Type

INTERVENTIONAL

Conditions

Refractive Error Correction Visual Acuity

Summary

This study seeks to determine whether glasses prescriptions determined from computer analysis of detailed images of the eyes provide better vision outcomes for children with Down syndrome than prescriptions determined using routine clinical methods.

Eligibility

Min Age: 5 YearsMax Age: 12 Years

Inclusion Criteria4

Down syndrome
Age 5 to 12 years
Ability to sit for study measures
Able to be dilated

Exclusion Criteria6

Nystagmus
History of Ocular or Refractive Surgery
Corneal or lenticular opacities
Ocular disease
Anisometropic or strabismic amblyopia
Contact allergy to aluminum

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

DEVICEMetric-optimized spectacles

Metric-optimized spectacles are glasses made from a prescription determined by the optimization of a metric for retinal image quality, Visual Strehl Ratio (VSX), as determined by algorithms utilizing wavefront aberration measures of the eye

DEVICERoutine Clinical Spectacles

Routine clinical spectacles are glasses made from a prescription based upon findings that are obtained during a routine eye examination, including autorefraction measures.