RecruitingPhase 4NCT07491367

Pilot Exploration of Platelet Characterization of Platelet Rich Plasma Created by Two Different Systems


Sponsor

University of California, San Francisco

Enrollment

20 participants

Start Date

Sep 1, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

The investigators would like to study the differences in the quality of Platelet Rich Plasma (PRP) between two different machines in those with knee osteoarthritis. Knee osteoarthritis means your cartilage has been worn down, and it affects your knee joint. Both machines, the APEX Biologix XCELL PRP System and the Emcyte PurePRP Supraphysiologic Concentrating System, are FDA approved, commercially available, and makes PRP. The investigators will check if the platelets in the PRP have different amounts or work differently. The investigators will also assess participants symptoms after the injection and compare the two different preparation systems.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a medical device called APEX Biologix XCELL PRP System, a medical device called Emcyte PurePRP Supraphysiologic Concentrating System, and others for people with cartilage damage, knee osteoarthristis, and other related conditions. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BIOLOGICALPlatelet Rich Plasma

The Platelet Rich Plasma (PRP) participants will receive in this study will be made by Emcyte PurePRP Supraphysiologic Concentrating System or the APEX Biologix XCELL PRP System.

DEVICEEmcyte PurePRP Supraphysiologic Concentrating System

Platelet Rich Plasma (PRP) will be made by the Emcyte PurePRP Supraphysiologic Concentrating System.

DEVICEAPEX Biologix XCELL PRP System

Platelet Rich Plasma (PRP) will be made by APEX Biologix XCELL PRP System.


Locations(1)

University of California San Francisco

San Francisco, California, United States

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NCT07491367


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