RecruitingNot ApplicableNCT07491601

PRESS -PAR: Early Detection and PREvention of Symptomatic postSurgical hypoPARathyroidism After Thyroid Surgery"


Sponsor

Nicolas Schlegel

Enrollment

336 participants

Start Date

Jan 8, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

This study aims to investigate whether an earlier measurement of parathyroid hormone can reduce the number of patients who develop symptomatic hypoparathyroidism. This will provide evidence for a clear algorithm to address this issue after thyroid surgery. It will lead to an improvement in quality of life and a reduction in the distress experienced by affected patients. In addition, it is conceivable that patients' hospital stay could be shortened.


Eligibility

Min Age: 18 Years

Inclusion Criteria3

  • Age ≥ 18 years
  • Thyroidectomy or bilateral thyroid resection of any indication
  • Written informed consent obtained after detailed patient information and provision of an information sheet

Exclusion Criteria7

  • Age ≤ 18 years
  • Concomitant parathyroid disease (primary or secondary hyperparathyroidism, pre-existing hypoparathyroidism of any cause)
  • Previous surgery in the neck region
  • Pregnancy or breastfeeding
  • Inability to attend study visits
  • Participation in another study that interferes with the endpoints
  • Missing or inadequate patient information

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Interventions

DRUGActive vitamin D

Application if parathyroid hormone level falls below normal

DRUGCalcium

Administered if parathyroid hormone level falls below normal


Locations(1)

Dept. Surgery I; University Hospital Wuerzburg

Würzburg, Bavaria, Germany

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NCT07491601


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