Manganese-enhanced Magnetic Resonance Imaging in Takotsubo Cardiomyopathy
University of Edinburgh
100 participants
Aug 8, 2025
INTERVENTIONAL
Conditions
Summary
The goal of this research study is to further understand the physiological mechanisms involved in a heart condition called takotsubo cardiomyopathy, also known as broken heart syndrome. Furthermore, the investigators will be assessing the effects different cardiac medications have on these physiological mechanisms. This will be achieved by performing cardiac MRI scans using a special dye called manganese. Manganese uptake in the heart is altered in patients with takotsubo cardiomyopathy. The investigators will study the effects that different cardiac medications have on manganese uptake.
Eligibility
Plain Language Summary
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Interventions
Participants will be randomised to receive Bisoprolol medication.
Participants will be randomised to receive Valsartan medication.
Participants will be randomised to receive Sacubitril/Valsartan medication first.
Participants will be randomised to receive Dapaglifozin medication first.
Participants will be randomised to receive no study medication.
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT07491718