RecruitingNot ApplicableNCT07492979

Conduction System Pacing vs. Biventricular Pacing for Cardiac Resynchronization Therapy

Nordic-CSP - a Randomized Nordic Study - Is Conduction System Pacing Superior Compared to Conventional BIV-CRT in Reducing the Death or Heart Failure-related Hospitalization in Patients With Heart Failure and Bundle Branch Block?

Sponsor

Rigshospitalet, Denmark

Enrollment

1,100 participants

Start Date

Jun 17, 2026

Study Type

INTERVENTIONAL

Conditions

Heart Failure Conduction System Pacing Cardiac Resynchronisation Therapy (CRT)

Summary

The NORDIC-CSP trial is an investigator-initiated, blinded, nordic RCT aimed at evaluating whether using direct pacing of the HIS bundle (HIS)-pacing or left bundle branch (LBB) pacing is superior to conventional biventricular pacing in reducing the incidence of the composite endpoint of death and non-planned HF hospitalization. The study will be conducted in the 4 CRT-centres in Denmark and 6-8 centres from countries Sweden, Norway and Finland.

Eligibility

Min Age: 18 YearsMax Age: 99 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a procedure called Conventional BiV-CRT and a procedure called HIS or LBBB -CRT for people with cardiac resynchronisation therapy (crt), conduction system pacing, and other related conditions. The study is currently recruiting participants at 5 locations. People eligible for this study include aged 18 Years to 99 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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