Trunk Inclination, Positive End-expiratory Pressure, and Lung Recruitability
Impact of Trunk Inclination on Lung Mechanics According to PEEP and Reruitability
Zhongda Hospital
40 participants
Mar 20, 2026
OBSERVATIONAL
Conditions
Summary
This multicenter, physiological, observational study hypothesizes that in moderate to severe ARDS, trunk inclination unloads the chest wall, but its impact on lung mechanics depends on PEEP levels and lung recruitability.
Eligibility
Plain Language Summary
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Interventions
Specific lung recruitment maneuvers will be performed to measure the potential for lung recruitment. Followed by a decremental PEEP steps to determine lung mechanics at different PEEP levels. These process will be repeated when patients change to another position. Electrical impedance tomography signals, synchronized signals of airway pressure and flow, esophageal pressure will be recorded continuously.
Locations(3)
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NCT07504731