Dexmedetomidine as an Adjuvant During Dural Puncture Epidural
The Effect of Different Doses of Dexmedetomidine as an Adjuvant to Bupivacaine for Parturients Having Dural Puncture Epidural Technique to Elaborate Labor Pain
Menoufia University
140 participants
Feb 1, 2026
INTERVENTIONAL
Conditions
Summary
The study aimed to determine the effects of using varied doses of DEX on the concentration of bupivacaine injected for epidural labor analgesia, and to assess the benefits of the dural puncture epidural.
Eligibility
Inclusion Criteria1
- Women who attend the Emergency Department in labor, with cervical dilation of 3-5 cm,
Exclusion Criteria6
- Abnormal fetal presentation or lie, 'premature rupture of membranes, maternal fever, fetal distress, pregnancy-induced diseases
- abnormal placental position,
- ASA grade>II
- marked obesity,
- allergy or contraindications to the used drugs,
- spinal deformity or disorders 'cutaneous diseases or infection at the injection site
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Interventions
epidural injection of plain Bup
the dura is punctured by a 26-G spinal needle using the needle-through-needle technique, and is withdrawn after confirmation of free-flowing cerebrospinal fluid,
Dexmedetomidine 0.4 added
Dexmedetomidine 0.6 added
Locations(1)
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NCT07506044