RecruitingNot ApplicableNCT07513818
Implementing Low-dose ct Lung Cancer Screening in France.
Sponsor
Assistance Publique - Hôpitaux de Paris
Enrollment
20,000 participants
Start Date
May 11, 2026
Study Type
INTERVENTIONAL
Conditions
Summary
The main objective is to estimate the detection rate of lung cancer in the population screened by low-dose chest CT scans.
Eligibility
Min Age: 50 YearsMax Age: 74 Years
Inclusion Criteria5
- Adults aged 50-74 years
- Active or former smoker having quit less than 15 years ago
- Smoking history of at least 20 pack-years, or 15 cigarettes/day for 25 years or 10 cigarettes/day for 30 years
- Affiliation with a social security scheme
- Written informed consent prior to study participation
Exclusion Criteria8
- Chest CT scan performed within the previous 12 months
- Signs of respiratory infection (fever, productive cough)
- Severe co-morbidities contraindicating exploration and/or management (including stereotactic surgery or radiotherapy) of lung cancers
- Poor general status (PS2 and above)
- Rest dyspnea (mMRC4)
- Cancer under active surveillance by thoracic computed tomography (CT pr PET-CT)
- Personal history of lung cancer
- Symptoms raising suspicion of lung cancer (hemoptysis, unexplained weight loss, recent onset or modification of respiratory symptoms,…)
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Interventions
PROCEDURELow-dose computed tomography of the chest
Baseline low-dose CT acquisition, then at 1 year and 3 years to depict suspicious lung nodules
Locations(2)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT07513818
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