RecruitingNot ApplicableNCT07513974

Objective Measurement of the Mechanical Pain Threshold With an Algometer for Predicting Intraoperative Opioid Consumption in Patients Who Will be Operate by Thoracotomy and Sternotomy in Cardiac Surgery

The Usefulness of Preoperative Measurement of the Mechanical Pain Threshold for Predicting Intraoperative Opioid Consumption


Sponsor

Université Libre de Bruxelles

Enrollment

100 participants

Start Date

Jan 24, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

The study aims to test the relationship between the preoperative pain threshold and the intraoperative need for opioids. The objective of the study is to try to predict a patient's analgesic needs based on their objectively determined preoperative pain threshold. The investigators will include patients scheduled for elective cardiovascular surgery. The investigators will investigate the correlation between the preoperative pain threshold and intraoperative/postoperative opioid consumption in a highly standardized anesthesia setting.


Eligibility

Inclusion Criteria1

  • ASA 3 patients with scheduled cardiac surgery by thoracotomy or sternotomy

Exclusion Criteria10

  • Patient refusal,
  • A body mass index (BMI) > 30 kg/m²,
  • Allergies to any medication used in typical cardiac anesthesia,
  • Chronic pain or regular use of analgesics,
  • Severe ventricular dysfunction, pulmonary hypertension, poorly controlled arhythmia,
  • Non-elective surgery.
  • Patients enrolled in another study protocol within the previous 3 months,
  • Pregnant or breastfeeding patients,
  • Patients with severe renal or hepatic impairment.
  • Patients for whom the study will be stopped in the event of blood loss greater than or equal to one liter, or for any other severe perioperative surgical complication.

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Interventions

DEVICEMeasure of the minimal pain threshold with an algometer

The measure of the minimal pain threshold is taken the day before the cardiac surgery


Locations(1)

Erasme Hospital

Brussels, Anderlecht, Belgium

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NCT07513974


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