RecruitingPhase 4NCT07515664

Vitamin K for Perioperative Warfarin Management

Vitamin K Reversal of INR for Perioperative Management of Warfarin: : A Pilot Study to Assess Feasibility

Sponsor

University of Michigan

Enrollment

20 participants

Start Date

Jul 3, 2025

Study Type

INTERVENTIONAL

Conditions

Anticoagulant Therapy

Summary

This is a feasibility study of uninterrupted warfarin with a one time dose of Vitamin K before a surgical procedure.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Vitamin K, a drug called Warfarin (standard with loading), and others for people with anticoagulant therapy. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGVitamin K

10 mg of oral vitamin K will be given approximately 36-48 hours before procedure.

DRUGWarfarin (standard without loading)

Patients receive their standard warfarin dosing without interruption.

DRUGWarfarin (standard with loading)

Patients receive their standard warfarin dosing without interruption; patients also receive a one time loading dose (twice normal dose) of warfarin on the evening following their procedure.