RecruitingNot ApplicableNCT07520487

Effect of Intravenous Ketamine Combined With Spinal Anesthesia on Sensory Block Duration Compared to Spinal Anesthesia Alone in Lower Limb Surgeries in Geriatrics.

Effect of Intravenous Ketamine Combined With Spinal Anesthesia on Sensory Block Duration Compared to Spinal Anesthesia Alone in Lower Limb Surgeries in Geriatrics: A Randomized Controlled Double-Blinded Trial.

Sponsor

Cairo University

Enrollment

61 participants

Start Date

Apr 25, 2026

Study Type

INTERVENTIONAL

Conditions

IV Ketamine With Spinal Block

Summary

Effect of Intravenous Ketamine combined with Spinal Anesthesia on Sensory Block Duration compared to Spinal Anesthesia alone in Lower Limb surgeries in geriatrics:

Eligibility

Min Age: 65 Years

Inclusion Criteria4

Patients aged 65 years and older
Both sexes
American Society of Anesthesiologists (ASA) physical status I, II, III
Scheduled for elective lower limb surgeries under spinal anesthesia in supine position

Exclusion Criteria5

Patient's refusal.
Pre-existing neurological disorders.
Coagulopathy (i.e., Platelets ≤ 60,000 and/or INR> 1.5).
Localized infection at the site of needle insertion.
Known hypersensitivity or allergies to any of the used drugs

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

DRUGPatients will receive 0.2 mg/kg IV of ketamine diluted to 5 ml followed by infusion 0.1 mg/kg/hr as a 20 ml solution

Patients will receive 0.2 mg/kg IV of ketamine diluted to 5 ml followed by infusion 0.1 mg/kg/hr as a 20 ml solution

DRUGPatients will receive 5 ml of saline followed by infusion 0.1 ml/kg/hr as a 20 ml solution as a control group

Patients will receive 5 ml of saline followed by infusion 0.1 ml/kg/hr as a 20 ml solution as a control group

Locations(1)

Cairo university hospitals

Cairo, Giza Governorate, Egypt

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT07520487