Comparison of the Effects of Sevoflurane and Desflurane on Optic Nerve Sheath Diameter During Laparoscopic Surgery
Comparison of the Effects of Sevoflurane and Desflurane Used for Anesthesia Maintenance on Optic Nerve Sheath Diameter in the Trendelenburg Position
Medipol University
60 participants
Apr 15, 2026
INTERVENTIONAL
Conditions
Summary
Laparoscopic surgeries require pneumoperitoneum and Trendelenburg position, which may lead to increased intracranial pressure (ICP). Optic nerve sheath diameter (ONSD) measurement via ultrasound is a non-invasive method to evaluate ICP. This prospective study aims to compare the effects of sevoflurane and desflurane on ONSD in patients undergoing laparoscopic hysterectomy and bilateral oophorectomy in the Trendelenburg position.
Eligibility
Inclusion Criteria1
- Patients planned for laparoscopic hysterectomy bilateral oophorectomy surgery under general anesthesia.
Exclusion Criteria5
- Patients receiving beta-blocker or diuretic treatment.
- Patients with severe heart failure.
- Patients diagnosed with diabetes with ocular or neurological complications.
- Patients who have undergone cardiac surgery, eye surgery, brain surgery, or thoracic surgery.
- Patients with a history of hydrocephalus, glaucoma, intracranial mass, and stroke.
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Interventions
Anesthesia maintenance will be provided with sevoflurane at 1 MAC in a 40% oxygen-air mixture.
Anesthesia maintenance will be provided with desflurane at 1 MAC in a 40% oxygen-air mixture.
Locations(1)
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NCT07525648