RecruitingPhase 1NCT07531316

Safety and Tolerability Study of VVZ-2471 in Healthy Volunteers

Sponsor

Virginia Commonwealth University

Enrollment

60 participants

Start Date

Aug 28, 2026

Study Type

INTERVENTIONAL

Conditions

Healthy (Controls)

Summary

The goal of this study is to do follow-up testing on the safety and tolerability of an experimental (not FDA approved) medication. This study is seeking non-illicit drug using adults to test the medication. Results of this study will help us to develop future studies to test the medication with people who use substances. This research is supported by and included in the NIH HEAL Initiative (https://heal.nih.gov/).

Eligibility

Min Age: 18 YearsMax Age: 65 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Placebo pills for 14-day intervention and a drug called VVZ-2471 for 14-day intervention for people with healthy (controls). The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years to 65 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGPlacebo pills for 14-day intervention

Subjects who are randomized to placebo will receive identical capsules to the study drug. During the 14-day intervention phase, participants will be instructed to take one capsule twice daily.

DRUGVVZ-2471 for 14-day intervention

100 mg/BID. Subjects who are randomized to VVZ-2471 will receive identical capsules to the placebo. During the 14-day intervention phase, participants will be instructed to take one capsule twice daily.