RecruitingPhase 2NCT07533942

A Study of JZP3507 (ONC206) in Recurrent Grade 2 or 3 Meningioma

A Phase 2 Study to Investigate Efficacy, Safety, Tolerability, and Pharmacokinetics of JZP3507 (ONC206) in Adults With Recurrent Grade 2 or 3 Meningioma


Sponsor

Jazz Pharmaceuticals

Enrollment

30 participants

Start Date

Jul 16, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

This study will recruit participants with Grade 2 and 3 meningiomas who have failed prior therapy. Participants will receive oral doses of JZP3507. The antitumor activity and safety of JZP3507 will be evaluated.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called JZP3507 for people with meningioma. The study is currently recruiting participants at 5 locations. People eligible for this study include aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGJZP3507

Participants will receive oral JZP3507 monotherapy twice daily, on 3 consecutive days per week in 28-day cycles.


Locations(5)

Sutter Health

San Francisco, California, United States

Louisiana State University

New Orleans, Louisiana, United States

Mass General

Boston, Massachusetts, United States

NYU- Langone Health

New York, New York, United States

University of Utah - Huntsman Cancer Institute

Salt Lake City, Utah, United States

View Full Details on ClinicalTrials.gov

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NCT07533942


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