RecruitingPhase 1NCT07533955

A Phase 1 Study of JADE201 in Participants With Rheumatoid Arthritis

A Phase 1, Randomized, Double-blind, Placebo-Controlled, Single Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of JADE201 Administered Subcutaneously in Participants With Rheumatoid Arthritis


Sponsor

Jade Biosciences, Inc.

Enrollment

36 participants

Start Date

May 19, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

This is a Phase 1, first in human study to evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of single ascending doses of JADE201 compared to placebo in participants with Rheumatoid Arthritis


Eligibility

Min Age: 18 YearsMax Age: 70 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called JADE201 and a drug called Placebo for people with rhematoid arthritis. The study is currently recruiting participants at 3 locations. People eligible for this study include aged 18 Years to 70 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGJADE201

JADE201 is supplied as sterile solution to be administered by SC injection.

DRUGPlacebo

Placebo solution to be administered at a matching volume by SC injection.


Locations(3)

Jade Clinical Site

Chisinau, Moldova, Moldova

Jade Clinical Site

Ivano-Frankivsk, Ukraine, Ukraine

Jade Clinical Site

Kyiv, Ukraine, Ukraine

View Full Details on ClinicalTrials.gov

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NCT07533955


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