The Effect of Paedfusor TCI, Eleveld TCI, and Sevoflurane Anesthesia on Postoperative Awakening Agitation in Pediatric Patients
Investigation of the Effects of Two Different TCI (Target Controlled Infusion) Models (Paedfusor and Eleveld) and Inhalation Anesthesia on Postoperative Awakening Agitation/Delirium in Pediatric Patients
Marmara University Pendik Training and Research Hospital
150 participants
Jan 13, 2026
INTERVENTIONAL
Conditions
Summary
Emergence delirium is a common complication in pediatric patients undergoing general anesthesia. The aim of this study is to investigate the incidence of postoperative awakening delirium and agitation in pediatric patients aged 3-10 years (ASA I-II) using two different target-controlled infusion (TCI) methods (Paedfusor and Eleveld) for TIVA, compared to inhalation anesthesia. This study will examine the effect of two different TCI models on postoperative awakening agitation/delirium by comparing them with each other and with inhalation anesthesia.
Eligibility
Inclusion Criteria5
- Children aged 3-10 years
- Children weighing over 10 kg
- American Society of Anesthesiologists (ASA) physical condition classification I-II
- Those who will undergo planned urogenital surgery under general anesthesia
- Those who have obtained written informed consent from their parents or legal guardians
Exclusion Criteria9
- Patients assessed as ASA III or higher
- Known neurological or psychiatric disorders
- Developmental delay or cognitive impairment
- Use of sedatives or psychoactive drugs
- Allergy or contraindication to the study drugs (propofol or sevoflurane)
- History of previous adverse reactions to anesthesia
- Patients requiring emergency surgery
- Significant liver, kidney, or cardiovascular disease
- Patients whose parents or legal guardians have not given consent
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Interventions
Propofol will be administered via target-controlled infusion using a Paedfusor model.
Propofol will be administered via target-controlled infusion using the Eleveld model.
Sevoflurane will be administered as an inhalation anesthetic.
Locations(2)
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NCT07534956