The Efficacy of Intradermal Acupuncture for Ocular Surface Diseases After Intractable Facial Paralysis
The First Affiliated Hospital of Zhejiang Chinese Medical University
78 participants
Apr 1, 2026
INTERVENTIONAL
Conditions
Summary
The purpose of this study is to explore the clinical efficacy of intradermal acupuncture in the treatment of ocular surface diseases after Intractable Facial Paralysis, and to seek effective and convenient treatment for ocular surface diseases after intractable peripheral facial paralysis. The main question it aims to answer is ： Will the intradermal acupuncture intervention effectively reduce the OSDI score ? The researchers compared the intradermal acupuncture with the placebo-needle to observe whether the intradermal acupuncture could better improve the symptoms.
Eligibility
Inclusion Criteria4
- Male or female patients aged 18-65 years.
- Meets diagnostic criteria for intractable peripheral facial paralysis, with disease duration from 1 month to 1 year. FNGS 2.0 ≥15 points; ENoG shows the ratio of CMAP amplitude≤ 20%.
- At least one subjective ocular symptom (dryness, foreign body sensation, burning, fatigue, redness, fluctuating vision) and OSDI scores between 30 and 80.
- Voluntarily provides written informed consent and can comply with treatment and follow-up.
Exclusion Criteria9
- Other ocular diseases (glaucoma, keratitis, retinopathy, acute inflammation of conjunctiva, sclera, cornea).
- \. Intraocular surgery or laser therapy within the past 90 days.
- Use of systemic or topical antibiotics or tear-affecting drugs within 3 weeks; dry eye medications within 2 weeks.
- Lacrimal passage obstruction, dacryocystitis, punctal occlusion, or neurological impairment preventing full eyelid closure.
- Coagulation disorders, open wounds, or local infection at intervention sites.
- Allergy to press-needle materials (stainless steel, adhesive tape).
- Pregnancy or lactation.
- Severe cardiac, hepatic, renal, psychiatric disorders, or malignant tumors.
- Participation in another clinical trial within the past month.
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Interventions
The IA group will receive basic background treatment. During the intervention phase, the group will receive IA treatment. After basic background treatment, IA treatment will adopt acupoints. Under strict aseptic conditions, a φ0.20\*1.2 mm IA(SEIRIN Co.,Japan) will puncture perpendicularly and retained in the skin.It will be retained for 72 hours and replaced twice weekly, with the entire intervention course lasting 4 weeks. During the IA treatment period, participants will perform standardized self-administered pressing by a dedicated WeChat mini program: 3 times daily, 3 minutes per session, 60 presses per minute, stimulating as much as tolerated.
The SIA group will receive basic background treatment. During the intervention phase, the group will receive SIA treatment.
Locations(1)
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NCT07537426