RecruitingNCT07538102

Respiratory Physiotherapy and Diaphragm Thickness in Ventilated ICU Patients

Effect of Respiratory Physiotherapy on Diaphragmatic Thickness in Mechanically Ventilated Patients in Intensive Care Unit: A Prospective Observational Controlled Trial


Sponsor

Hitit University

Enrollment

66 participants

Start Date

Aug 1, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

This study aims to evaluate the effect of respiratory physiotherapy on diaphragm thickness in patients receiving mechanical ventilation support in the intensive care unit. Thinning and dysfunction of the diaphragm muscle observed during mechanical ventilation complicate the extubation process and increase the risk of respiratory failure in patients. Diaphragm dysfunction prolongs ventilator use and increases ICU mortality. The main objective of this research is to determine whether respiratory physiotherapy has protective or ameliorative effects on diaphragm muscle structure and function, to optimize the ventilator weaning process, and to provide scientific contributions to the field of respiratory rehabilitation. Changes in diaphragm thickness will be objectively evaluated using ultrasonography, and the aim is to obtain evidence-based data on the effectiveness of respiratory physiotherapy.


Eligibility

Min Age: 18 Years

Inclusion Criteria5

  • Age ≥ 18 years
  • Mechanically ventilated for at least 5 days
  • Hemodynamically stable
  • Unconscious (Glasgow Coma Scale indicating impaired consciousness)
  • Informed consent obtained from legal representatives

Exclusion Criteria6

  • Neuromuscular disease
  • Traumatic diaphragm injury
  • Thoracic deformity causing mechanical impairment of respiration
  • Terminal-stage patients
  • Patients in whom respiratory physiotherapy is contraindicated
  • Presence of a cardiac pacemaker or implantable cardioverter-defibrillator (ICD)

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Interventions

OTHERStandard ICU Physiotherapy

Standard ICU physiotherapy applied once daily for 15-20 minutes.

DEVICENeuromuscular Electrical Stimulation (NMES)

NMES applied to the diaphragmatic region twice daily, in addition to standard ICU physiotherapy.


Locations(1)

Hitit University

Çorum, Centre, Turkey (Türkiye)

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NCT07538102


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