Respiratory Physiotherapy and Diaphragm Thickness in Ventilated ICU Patients
Effect of Respiratory Physiotherapy on Diaphragmatic Thickness in Mechanically Ventilated Patients in Intensive Care Unit: A Prospective Observational Controlled Trial
Hitit University
66 participants
Aug 1, 2025
OBSERVATIONAL
Conditions
Summary
This study aims to evaluate the effect of respiratory physiotherapy on diaphragm thickness in patients receiving mechanical ventilation support in the intensive care unit. Thinning and dysfunction of the diaphragm muscle observed during mechanical ventilation complicate the extubation process and increase the risk of respiratory failure in patients. Diaphragm dysfunction prolongs ventilator use and increases ICU mortality. The main objective of this research is to determine whether respiratory physiotherapy has protective or ameliorative effects on diaphragm muscle structure and function, to optimize the ventilator weaning process, and to provide scientific contributions to the field of respiratory rehabilitation. Changes in diaphragm thickness will be objectively evaluated using ultrasonography, and the aim is to obtain evidence-based data on the effectiveness of respiratory physiotherapy.
Eligibility
Inclusion Criteria5
- Age ≥ 18 years
- Mechanically ventilated for at least 5 days
- Hemodynamically stable
- Unconscious (Glasgow Coma Scale indicating impaired consciousness)
- Informed consent obtained from legal representatives
Exclusion Criteria6
- Neuromuscular disease
- Traumatic diaphragm injury
- Thoracic deformity causing mechanical impairment of respiration
- Terminal-stage patients
- Patients in whom respiratory physiotherapy is contraindicated
- Presence of a cardiac pacemaker or implantable cardioverter-defibrillator (ICD)
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Interventions
Standard ICU physiotherapy applied once daily for 15-20 minutes.
NMES applied to the diaphragmatic region twice daily, in addition to standard ICU physiotherapy.
Locations(1)
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NCT07538102