RecruitingNot ApplicableNCT07538388

Continuous Versus Bolus Norepinephrine Administration to Treat Postinduction Hypotension

Continuous Versus Bolus Norepinephrine Administration to Treat Postinduction Hypotension in High-Risk Non-Cardiac Surgery Patients - The Multicenter INDUCT Trial (INDUCT-Multi)

Sponsor

Universitätsklinikum Hamburg-Eppendorf

Enrollment

446 participants

Start Date

May 7, 2026

Study Type

INTERVENTIONAL

Conditions

Postinduction Hypotension

Summary

INDUCT-Multi is a multicenter randomized trial investigating whether continuous, compared to bolus, administration of norepinephrine during induction of general anesthesia reduces postinduction hypotension in high-risk non-cardiac surgery patients.

Eligibility

Min Age: 45 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a procedure called Continuous Norepinephrine Administration for people with postinduction hypotension. The study is currently recruiting participants at 4 locations. People eligible for this study include aged 45 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

PROCEDUREContinuous Norepinephrine Administration

In patients assigned to continuous administration of norepinephrine, a syringe infusion pump will be prepared and connected to a peripheral or central venous catheter. The responsible anesthesiologist will start the norepinephrine infusion and adjust the infusion rate as necessary and may administer additional norepinephrine boluses via the syringe infusion pump if required.

Locations(4)

Department of Anesthesiology and Intensive Care Medicine, Campus Benjamin Franklin, Charité - Universitätsmedizin Berlin

Berlin, Germany

Department of Anesthesiology, University Hospital Duesseldorf, Heinrich Heine University Duesseldorf

Düsseldorf, Germany

Department of Anesthesiology, Center of Anesthesiology and Intensive Care Medicine, University Medical Center Hamburg-Eppendorf

Hamburg, Germany

Department of Anaesthesiology, University Hospital LMU Munich

München, Germany

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT07538388