RecruitingNot ApplicableNCT07541924

The Impact of Image-Assisted Colonoscope on Patient Experience, Physician Workload, and Examination Quality


Sponsor

DONG WU

Enrollment

200 participants

Start Date

Dec 9, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

Colonoscopy is the cornerstone for colorectal cancer screening, diagnosis, and post-treatment surveillance. Procedural quality is influenced by patient anatomy, particularly variations in colonic configuration such as sigmoid redundancy, looping, and low-lying transverse colon. These features prolong insertion time, increase patient discomfort, and elevate physician workload. Evidence suggests that prior CT imaging can provide objective and individualized information on colonic anatomy-such as redundancy, angulation, and tortuosity-potentially predicting procedural difficulty. However, existing studies are mainly retrospective or descriptive, lacking prospective randomized evidence on clinical utility. This single-blind, randomized controlled trial evaluates whether image-assisted colonoscope insertion, based on pre-existing abdominal/pelvic CT scans, can improve cecal intubation time, enhance patient experience, reduce operator workload, and improve overall examination quality compared with standard colonoscopy.


Eligibility

Min Age: 18 YearsMax Age: 80 Years

Inclusion Criteria4

  • Age 18-80 years, or expected natural survival >3 years
  • Undergoing colonoscopy at Peking Union Medical College Hospital
  • Presence of an abdominal/pelvic CT scan performed within ≤5 years and no - - - major abdominal surgery afterward
  • Patient or legal guardian able to understand the study and provide written consent

Exclusion Criteria6

  • No available CT or CT quality insufficient for anatomical evaluation
  • Prior colonic surgery affecting anatomy (e.g., right hemicolectomy, transverse colectomy)
  • Severe cardiopulmonary dysfunction or coagulopathy
  • Pregnancy
  • Refusal to participate or inability to complete questionnaires
  • Patient or guardian unable to understand study requirements

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Interventions

OTHERCT-Based Image-Assisted Colonoscope Insertion

This intervention uses pre-existing abdominal or pelvic CT imaging (within 5 years, without major abdominal surgery) to assess individual colonic morphology prior to colonoscopy. Key CT-derived features include colonic redundancy, looping patterns, fixation points, and segmental angulation. Based on these findings, the endoscopist receives a structured, standardized briefing before colonoscope insertion, including predicted difficult segments and recommended insertion strategies. No additional imaging, radiation, or invasive procedures are used. The intervention aims to improve insertion efficiency, reduce patient discomfort, and lower operator workload compared with standard colonoscopy without image guidance.


Locations(1)

Peking Union Medical College Hospital

Beijing, Beijing Municipality, China

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NCT07541924


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