RecruitingNot ApplicableNCT07542028

Comparison of the Analgesic Effects of TFPB in Renal Transplantation Surgery

Comparison of the Analgesic Effects of Transversalis Fascia Plane Block in Renal Transplantation Surgery


Sponsor

Ankara Etlik City Hospital

Enrollment

50 participants

Start Date

Apr 27, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

Renal transplantation is a major surgical procedure associated with significant postoperative pain, particularly due to lower abdominal incision, deep tissue dissection, and extensive surgical manipulation. Effective postoperative pain control is therefore of great importance in this patient population, as inadequate analgesia may impair early mobilization, delay recovery, increase opioid consumption, and contribute to opioid-related adverse effects. In addition, optimal analgesic management may improve patient comfort and support enhanced postoperative outcomes. Nerve blocks reduces opioid consumption in the postoperative period by providing better pain control and therefore has advantages such as fewer side effects and less risk of pulmonary and cardiac complications. In this study; it was aimed to compare the analgesic effectiveness of transversalis fascia plane block in the postoperative period in patients who underwent renal transplantation.


Eligibility

Min Age: 18 YearsMax Age: 65 Years

Inclusion Criteria3

  • Patients aged 18-65 years
  • American Society of Anesthesiologists (ASA) score III
  • Body Mass Index (BMI) between 18-30 kg/m2

Exclusion Criteria4

  • Patients under 18 and over 65 years of age
  • Patients with an ASA score other than III
  • Patients with a history of bleeding diathesis
  • BMI below 18 or above 30 kg/m2

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Interventions

PROCEDURETransversalis Fascia Plane Block Group

This procedure will be performed unilaterally on the surgical side. 30 ml of 0.25% bupivacaine will be injected for ultrasound-guided transversalis fascia plane block application. The standard intraoperative analgesic regimen will consist of intravenous tramadol (1 mg/kg) administered both before the incision and at the end of the procedure, with intravenous paracetamol (10 mg/kg) given exclusively at the end of the surgery.

PROCEDUREControl Group

No peripheral nerve block will be performed. The standard intraoperative analgesic regimen will consist of intravenous tramadol (1 mg/kg) administered both before the incision and at the end of the procedure, with intravenous paracetamol (10 mg/kg) given exclusively at the end of the surgery.


Locations(1)

Atakan Sezgi

Altındağ, Ankara, Turkey (Türkiye)

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NCT07542028


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