RecruitingNot ApplicableNCT07546864

Comparative Effects of Mirror Therapy and Cognitive Orientation to Daily Occupational Performance in Stroke: A Randomized Controlled Trial

Comparative Effects of Mirror Therapy, Cognitive Orientation to Daily Occupational Performance, and Conventional Occupational Therapy in Individuals With Stroke: A 3-Month Follow-Up Randomized Controlled Trial

Sponsor

Hacettepe University

Enrollment

45 participants

Start Date

Feb 15, 2026

Study Type

INTERVENTIONAL

Conditions

Stroke Stroke Rehabilitaion

Summary

This study aims to compare the effectiveness of three rehabilitation approaches in individuals with stroke: mirror therapy (MT), cognitive orientation to daily occupational performance (CO-OP), and conventional occupational therapy (COT), all combined with robotic balance training. A total of 45 individuals with subacute and chronic stroke will be randomly assigned to one of three groups. Each group will receive 4 weeks of intervention (5 sessions per week), followed by a 3-month follow-up period. Outcomes related to motor function, somatosensory function, activities of daily living, participation, and quality of life will be assessed at baseline, after intervention, and at follow-up. The study aims to determine which intervention approach is more effective in improving functional outcomes in individuals with stroke.

Eligibility

Min Age: 18 Years

Inclusion Criteria8

\- Individuals diagnosed with ischemic or hemorrhagic stroke
Age 18 years and older
Subacute (3-6 months post-stroke) or chronic stage (6-12 months post-stroke)
Brunnstrom Motor Recovery Stage ≥3 for upper extremity, ≥4 for hand, and ≥4 for lower extremity
Mini-Mental State Examination (MMSE) score ≥24
No severe visual, orthopedic, or additional neurological impairments
Not participating in another study during the research period
Voluntary consent to participate in the study

Exclusion Criteria4

\- Poor motor coordination or major medical problems that would prevent participation
Presence of Wernicke's aphasia
Botulinum toxin injection within the last 3 months
Psychiatric conditions that may interfere with participation (e.g., depression, ongoing psychiatric treatment, low motivation)

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Interventions

BEHAVIORALMirror Therapy

Mirror therapy involves the use of a mirror to create a visual illusion of movement of the affected limb by observing the reflection of the unaffected limb. Task-oriented activities are performed to improve motor function and sensory integration in individuals with stroke.

BEHAVIORALCognitive Orientation to Daily Occupational Performance (CO-OP)

CO-OP is a client-centered, performance-based approach that uses cognitive strategies to enable skill acquisition. Participants identify meaningful goals and use guided discovery and problem-solving strategies to improve task performance.

BEHAVIORALConventional Occupational Therapy

Conventional occupational therapy includes task-oriented interventions such as reaching, grasping, coordination training, strengthening exercises, and activities aimed at improving functional independence in daily living.

OTHERRobotic Balance Training

Robotic balance training is used as a priming intervention before therapy sessions. It includes repetitive, task-specific movements involving weight shifting, postural control, and balance training to enhance motor responses.